DST Inspire Fellow developing Biomaterials for Bone Tissue Regeneration

New Delhi: The lab of this recipient of Inspire fellowship instituted by the Department of Science & Technology (DST), Government of India, is amongst the very few labs in India who are working with stem cells derived from gums around the teeth technically called human gingiva. Bone marrow, dental pulp, alveolar bone, periodontal ligament, umbilical cord, endometrium, breast milk, and adipose tissue are the major and well-studied sources of stem cells. Therefore, her group aims at establishing gingiva to be at par with the other stem cell sources, as it is very easy to harvest and involves minimum invasion into the host system. Her group is also working in close collaboration with some of the developing labs in and around Pune to establish stem cell facilities for commercialization of stem cell therapies.

 

Currently placed as a DST Women scientist (WOS- B), she has developed a polymer system for replicating the bone marrow microenvironment by co-culturing bone cells on its surface. This would enable the researchers in therapeutic screening of the target molecules. Along with her group, she is currently working on development of a hydrogel-based cell-seeded scaffold to design a minimally invasive regenerative approach for vertebral and inter-vertebral disorders. She has started the process for patenting of this technology and is also working as a consultant for many industries for development of therapeutic products.

 

Dr. Geetanjali’sTEDx talk regarding genetic engineering approaches for therapeutics had gained her accolades.

 

Publication details:

 

G.B Tomar*, J.R Dave, S.S Chandekar, N Bhattacharya, S Naik, S Kulkarni, S Math, K.U Desai, N.B Sapkal. 2020. Advances in Tissue Engineering Approaches for Craniomaxillofacial Bone Reconstruction. Tissue Engineering and the 5 R’s Reconstruction, Restoration, Replacement, Repair, and Regeneration. Intech Open. https://doi.org/10.5772/intechopen.94340

 

S.E More, J.R Dave, P.K Makar, S.V Bhoraskar, S. Premkumar, G.B Tomar*, V.L Mathe*. 2020. Surface modification of UHMWPE using ECR plasma for osteoblast and osteoclast differentiation. Applied Surface Science 506: 144665. https://doi.org/10.1016/j.apsusc.2019.144665 [IF: 5.155].

 

J.R Dave, A.M Dewle, S.T Mhaske, P.T Phulpagar, V.L Mathe, S.E More, A.A Khan, A.V.R Murthy, S.S Datar, A.J Jog, M. Page, G.B Tomar*. 2019. Hydroxyapatite nanorods loaded with parathyroid hormone (PTH) synergistically enhance the net formative effect of PTH anabolic therapy. Nanomedicine: Nanotechnology, Biology and Medicine 15(1) 218-230. https://doi.org/10.1016/j.nano.2018.10.003 [IF: 6.69; Citations: 5].

 

T Bennur, V Javdekar, G.B Tomar*, SmitaZinjarde*. 2020. Gold nanoparticles biosynthesized by Nocardiopsisdassonvillei NCIM 5124 enhance osteogenesis in gingival mesenchymal stem cells. Applied Microbiology and Biotechnology 104: 4081–4092.
https://doi.org/10.1007/s00253-020-10508-z

*Corresponding Author

For further details, Dr. GeetanjaliTomar(Email: geetanjalitomar13@gmail.com; joshigeet@gmail.com ) may be contacted

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