Penn Medicine

Penn Medicine researchers are seeking new biomarkers for traumatic brain injury (TBI), with the hope of testing new TBI treatments in clinical trials. By understanding the underlying pathology of different brain injuries and how they cause…

Lidocaine—often used as numbing agent for outpatient medical procedures—activates certain bitter taste receptors through two unique mechanisms that result in cancer cell death, according to researchers from the Perelman School of Medicine…

Robin Wood, PhD, RN, senior clinical director at the Hospital of the University of Pennsylvania (HUP) Capacity Management Center and the Penn Medicine Transfer Center in the University of Pennsylvania Health System (UPHS), has been…

The number of patients admitted with opioid use disorder (OUD) and injection-related infections who left the hospital before completing treatment increased significantly between 2016 and 2020 (from 9.3 percent to 17 percent) according…

Early results from a Phase I clinical trial of AT101, a new CAR T cell therapy that uses a distinct binding mechanism to target CD19, show a 100 percent complete response (CR) rate at the higher dose levels studied in the trial, according…

Non-Hispanic Black patients with acute myeloid leukemia (AML) are living longer, now that new therapies are available, according to a study presented by researchers from the University of Pennsylvania Perelman School of Medicine and Penn…

For thousands of people around the world waiting for a kidney, paired exchange serves as a beacon of hope. One person's willingness to undergo the act of Kidney Paired Donation (KPD) often sets in motion a chain of beautiful and selfless…

Having the ability to self-schedule mammograms was associated with a 15 percentage point increase following through with getting the screening, according to research from the Perelman School of Medicine at the University of Pennsylvania.…

New research reveals that neurons in the preoptic hypothalamus—the region of the brain that regulates sleep and body temperature—are rhythmically activated during non-rapid eye movement sleep (NREM). Stress activates these brain cells out…

A “chaperone” molecule that slows the formation of certain proteins reversed disease signs, including memory impairment, in a mouse model of Alzheimer’s disease, according to a study from researchers at the Perelman School of Medicine at…