Utrecht University: Human health may be at risk from long-term exposure to air pollution below current air quality standards and guidelines

Researchers found evidence of higher death rates amongst people who had been exposed to more air pollution even though the levels were allowed under current official standards. Previous studies have found an association between long term exposure to outdoor air pollution such as those in the form of fine particles in the air (known as particulate matter) and nitrogen dioxide and poor health or death. Professor Bert Brunekreef external link: “Our study contributes to the evidence that outdoor air pollution is associated with mortality even at levels below the current European and North American standards and WHO guideline values. These findings are therefore an important contribution to the debate about revision of air quality limits, guidelines and standards, and future assessments by the Global Burden of Disease.”

Our study confirms that outdoor air pollution is associated with mortality even at levels below the current air quality standards and guidelines

More likely to die
Low level air pollution was defined as concentrations below current limit values as set by the European Union, US Environmental Protection Agency and the World Health Organization (WHO) air quality guidelines. The researchers analysed data on eight groups of people within six European countries – Sweden, Denmark, France, the Netherlands, Germany and Austria – totalling 325,367 adults collectively. Their study recruited participants in the 1990s or 2000s. Of the 325,367 participants who were followed up over an almost 20-year period, around 14.5% (47,131 people) died during the study period. Analysis of the results showed that people who had higher exposure to particulate matter, nitrogen dioxide, and black carbon were more likely to die.

People who had higher exposure to air pollution were more likely to die

Increase of natural deaths
An increase of 5 µg/m3 of particulate matter was associated with a 13% increase in natural deaths while the corresponding figure for a 10 µg/m3 increase in nitrogen dioxide was 8.6%. Associations with particulate matter and nitrogen dioxide were largely independent of each other. Moreover, associations with particulate matter, nitrogen dioxide, and black carbon remained significant at low to very low concentrations.
For people who were exposed to pollution levels below the US standard of 12 µg/m3, an increase of 5 µg/m3 in particulate matter was associated with a 29.6% increase in natural deaths. People exposed to nitrogen dioxide at less than half the current EU standard of 40 µg/m3, a 10 µg/m3 increase in nitrogen dioxide was associated with a 9.9% increase in natural deaths. This is an observational study, and as such, can’t establish cause.

Large study
The study also has some limitations, such as the fact that it focused on exposure in 2010 which was towards the end of the follow-up period for most participants and, given the downward trend in air pollution, this measure might not exactly reflect the concentrations experienced during follow-up. However, this was a large study from multiple European groups of people with detailed information provided.

Unclear whether there was a link
Air pollution concentrations have fallen substantially in Europe since the 1990s, but it was unclear whether there still was a link between pollution and ill health or death at concentrations of pollution that are below current permitted limits. Therefore, an international team of researchers led by the Institute for Risk Assessment Sciences at Utrecht University in the Netherlands, set out to investigate if there was an association between low levels of air pollution concentrations and natural and cause specific deaths.

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